Severe Asthma Research Program (SARP)
A National Institutes of Health/ National Heart, Lung & Blood Institutes
sponsored network
Investigators at The Cleveland Clinic, Emory University and The University of Virginia lead a collaborative effort to study the reducing and oxidizing chemistry in the airways of adults and children with severe asthma. Studies reveal that biochemical disorders are characteristic of severe asthma and include: (1) impaired regulation of airway acidity, (2) loss of antioxidant capacity, and (3) loss of beneficial chemical forms of nitric oxide. The Emory site has focused on severe asthma in pediatric-age patients, so as to understand the origin of severe asthma early in life, and how it changes over time. The overall goal of the Cleveland Clinic-Emory-UVA consortium is to discover and test new treatments for severe asthma, which target the airway redox chemical pathways.
Cleveland Clinic
Serpil Erzurum, MD (Principal Investigator)
Link to web page
Interested in Participating in SARP?