Severe Asthma Research Program (SARP)
A National Institutes of Health/ National Heart, Lung & Blood Institutes
sponsored network
Investigators at The Cleveland Clinic, Emory University and The
University of Virginia lead a collaborative effort to study the
reducing and oxidizing chemistry in the airways of adults and children
with severe asthma. Studies reveal that biochemical disorders are
characteristic of severe asthma and include: (1) impaired regulation of
airway acidity, (2) loss of antioxidant capacity, and (3) loss of
beneficial chemical forms of nitric oxide. The Emory site has focused
on severe asthma in pediatric-age patients, so as to understand the
origin of severe asthma early in life, and how it changes over time.
The overall goal of the Cleveland Clinic-Emory-UVA consortium is to
discover and test new treatments for severe asthma, which target the
airway redox chemical pathways.
Emory University
Anne Fitzpatrick, PhD (co-investigator)
Interested in Participating in SARP?