PARTICIPATE IN SARP  University of Wisconsin - Madison

Our main focus is on the role of respiratory infections, particularly rhinovirus, in severe asthma. It is thought that in some individuals, severe asthma is caused by an infection with strains of rhinovirus that result in changes in the airway environment. This change can produce reduced anti-viral activity allowing for persistent infection, inflammation and obstruction in the airway. We are also investigating the contribution of airway abnormalities in airflow obstruction through pulmonary function testing and lung imaging. Though significant advances have been made to identify distinguishing features of severe asthma, there are still a number of key questions that remain in order to establish mechanisms of this asthma phenotype and improve treatment. The project at the University of Wisconsin will focus on the role of respiratory infections in severe asthma.

 

William Busse, MD (Principal Investigator)

Nizar Jarjour, MD (Co-Investigator)

Interested in Participating in SARP?

You will likely qualify for participation in SARP as a severe asthmatic if you:
1.    Have been diagnosed with asthma by a physician
2.    Require high  or continuous doses of asthma medications, such as Advair, Symbicort, prednisone or medrol
3.    Still have asthma symptoms on a regular basis
4.    Have had frequent or severe exacerbations of asthma (requiring prednisone,  ER visits, hospitalizations)
5.    Are not currently smoking and have smoked less than 5-10 years total
6.    Are between the ages of 6 yrs and 75 yrs of age

You may also qualify for participation in SARP as a “comparative” patient with mild asthma.     Similarly, you must be diagnosed with asthma, be between 6 and 75 yrs of age and not be currently smoking or have smoked for more than 5-10 yrs

PARTICIPATE IN SARP  University of Wisconsin - Madison